# IUPred2A: context-dependent prediction of protein disorder as a function of redox state and protein binding # Balint Meszaros, Gabor Erdos, Zsuzsanna Dosztanyi # Nucleic Acids Research 2018;46(W1):W329-W337. # # Prediction type: long # Prediction output # POS RES IUPRED2 1 M 0.0690 2 V 0.0749 3 S 0.0483 4 K 0.0631 5 M 0.0835 6 I 0.0531 7 I 0.0398 8 E 0.0518 9 N 0.0631 10 F 0.0817 11 E 0.0631 12 A 0.0799 13 L 0.1424 14 K 0.0929 15 S 0.0646 16 W 0.0817 17 L 0.1184 18 S 0.1914 19 K 0.2064 20 T 0.1914 21 L 0.2783 22 E 0.2002 23 P 0.2064 24 I 0.2752 25 C 0.2064 26 D 0.1583 27 A 0.1791 28 D 0.2258 29 P 0.1702 30 S 0.1323 31 A 0.1275 32 L 0.1823 33 A 0.1823 34 K 0.1554 35 Y 0.2224 36 V 0.2988 37 L 0.2849 38 A 0.3149 39 L 0.2436 40 V 0.2094 41 K 0.1969 42 K 0.1643 43 D 0.1643 44 K 0.1298 45 S 0.1399 46 E 0.2164 47 K 0.2129 48 E 0.2849 49 L 0.2575 50 K 0.2328 51 A 0.2328 52 L 0.2541 53 C 0.2541 54 I 0.2470 55 D 0.2575 56 Q 0.2752 57 L 0.2064 58 D 0.1373 59 V 0.1007 60 F 0.1476 61 L 0.1501 62 Q 0.1206 63 K 0.1048 64 E 0.1528 65 T 0.1969 66 Q 0.1528 67 I 0.1554 68 F 0.2129 69 V 0.2064 70 E 0.2575 71 K 0.2817 72 L 0.2849 73 F 0.2988 74 D 0.3286 75 A 0.3529 76 V 0.3494 77 N 0.3494 78 T 0.4369 79 K 0.5342 80 S 0.5951 81 Y 0.5992 82 L 0.5992 83 P 0.5992 84 P 0.7209 85 P 0.6531 86 E 0.6712 87 Q 0.6183 88 P 0.4940 89 S 0.5211 90 S 0.5342 91 G 0.5533 92 S 0.6322 93 L 0.7080 94 K 0.6712 95 V 0.5577 96 E 0.5254 97 F 0.5296 98 F 0.5055 99 P 0.4685 100 H 0.4186 101 Q 0.4220 102 E 0.4186 103 K 0.4087 104 D 0.4619 105 I 0.4541 106 K 0.4979 107 K 0.4940 108 E 0.5992 109 E 0.7163 110 I 0.5707 111 T 0.5620 112 K 0.5382 113 E 0.5382 114 E 0.4831 115 E 0.4979 116 R 0.5807 117 E 0.5854 118 K 0.6269 119 K 0.6755 120 F 0.7080 121 S 0.7718 122 R 0.7718 123 R 0.7718 124 L 0.7755 125 N 0.7289 126 H 0.7331 127 S 0.7289 128 P 0.7595 129 P 0.7505 130 Q 0.7547 131 S 0.8375 132 S 0.8343 133 S 0.8313 134 R 0.8313 135 Y 0.8792 136 R 0.8655 137 E 0.8565 138 N 0.8530 139 R 0.8198 140 S 0.7916 141 R 0.7672 142 D 0.7672 143 E 0.7595 144 R 0.7595 145 K 0.7080 146 K 0.7672 147 D 0.7718 148 D 0.7982 149 R 0.8085 150 S 0.8421 151 R 0.8375 152 K 0.8421 153 R 0.8421 154 D 0.8530 155 Y 0.8085 156 D 0.8085 157 R 0.8085 158 N 0.8085 159 P 0.7595 160 P 0.7799 161 R 0.7799 162 R 0.7799 163 D 0.7799 164 S 0.7951 165 Y 0.7916 166 R 0.8421 167 D 0.8375 168 R 0.8462 169 Y 0.7799 170 N 0.7505 171 R 0.7163 172 R 0.7209 173 R 0.7209 174 G 0.7209 175 R 0.7163 176 S 0.7755 177 R 0.6227 178 S 0.6227 179 Y 0.6269 180 S 0.6851 181 R 0.6620 182 S 0.6089 183 R 0.6089 184 S 0.6043 185 R 0.5854 186 S 0.5854 187 W 0.5807 188 S 0.5854 189 K 0.5758 190 E 0.6427 191 R 0.6322 192 L 0.6427 193 R 0.6375 194 E 0.6427 195 R 0.6375 196 D 0.6482 197 R 0.6375 198 D 0.7951 199 R 0.7881 200 S 0.7881 201 R 0.7916 202 T 0.7881 203 R 0.8279 204 S 0.8279 205 R 0.7916 206 S 0.7629 207 R 0.7718 208 T 0.7982 209 R 0.8050 210 S 0.7505 211 R 0.7459 212 E 0.6991 213 R 0.6948 214 D 0.6948 215 L 0.6948 216 V 0.6991 217 K 0.7250 218 P 0.6755 219 K 0.6661 220 Y 0.6906 221 D 0.7036 222 L 0.6322 223 D 0.6482 224 R 0.6806 225 T 0.6427 226 D 0.6991 227 P 0.7331 228 L 0.6906 229 E 0.6906 230 N 0.6906 231 N 0.6991 232 Y 0.7036 233 T 0.7595 234 P 0.7718 235 V 0.7755 236 S 0.7036 237 S 0.7331 238 V 0.6576 239 P 0.7415 240 S 0.7547 241 I 0.6806 242 S 0.6712 243 S 0.7415 244 G 0.7459 245 H 0.6482 246 Y 0.6991 247 P 0.6531 248 V 0.5807 249 P 0.6089 250 T 0.6043 251 L 0.6136 252 S 0.6806 253 S 0.6755 254 T 0.6851 255 I 0.6948 256 T 0.7080 257 V 0.7881 258 I 0.7718 259 A 0.8125 260 P 0.7951 261 T 0.6531 262 H 0.7163 263 H 0.7209 264 G 0.6089 265 N 0.6043 266 N 0.6851 267 T 0.6991 268 T 0.7672 269 E 0.7843 270 S 0.8085 271 W 0.7916 272 S 0.7951 273 E 0.7982 274 F 0.7120 275 H 0.6482 276 E 0.6322 277 D 0.6375 278 Q 0.6531 279 V 0.6183 280 D 0.6322 281 H 0.6269 282 N 0.7672 283 S 0.7672 284 Y 0.6531 285 V 0.7629 286 R 0.7881 287 P 0.6851 288 P 0.6948 289 M 0.6851 290 P 0.7331 291 K 0.7289 292 K 0.6183 293 R 0.5017 294 C 0.4766 295 R 0.5620 296 D 0.6322 297 Y 0.6661 298 D 0.6089 299 E 0.4864 300 K 0.5254 301 G 0.4186 302 F 0.4476 303 C 0.4507 304 M 0.4582 305 R 0.5533 306 G 0.5807 307 D 0.5707 308 M 0.6183 309 C 0.5382 310 P 0.4725 311 F 0.4979 312 D 0.5176 313 H 0.5577 314 G 0.6906 315 S 0.6576 316 D 0.6712 317 P 0.6712 318 V 0.5992 319 V 0.5707 320 V 0.7036 321 E 0.5665 322 D 0.7036 323 V 0.6482 324 N 0.6851 325 L 0.6948 326 P 0.7120 327 G 0.6183 328 M 0.5419 329 L 0.6269 330 P 0.7036 331 F 0.7755 332 P 0.7672 333 A 0.7547 334 Q 0.8198 335 P 0.8198 336 P 0.8235 337 V 0.8235 338 V 0.8279 339 E 0.8713 340 G 0.9151 341 P 0.9168 342 P 0.9308 343 P 0.8942 344 P 0.9081 345 G 0.9039 346 L 0.9039 347 P 0.9039 348 P 0.9057 349 P 0.9381 350 P 0.8966 351 P 0.8942 352 I 0.8942 353 L 0.8942 354 T 0.8462 355 P 0.8462 356 P 0.8530 357 P 0.8991 358 V 0.8966 359 N 0.8966 360 L 0.8462 361 R 0.8462 362 P 0.8462 363 P 0.8991 364 V 0.8966 365 P 0.9039 366 P 0.9039 367 P 0.8596 368 G 0.8530 369 P 0.8966 370 L 0.8991 371 P 0.9346 372 P 0.9396 373 S 0.9396 374 L 0.9039 375 P 0.9381 376 P 0.9381 377 V 0.9013 378 T 0.9081 379 G 0.9126 380 P 0.9039 381 P 0.9381 382 P 0.9151 383 P 0.9211 384 L 0.9081 385 P 0.9457 386 P 0.9457 387 L 0.9433 388 Q 0.9649 389 P 0.9547 390 S 0.9547 391 G 0.9488 392 M 0.9433 393 D 0.9106 394 A 0.9126 395 P 0.9433 396 P 0.9106 397 N 0.8681 398 S 0.9081 399 A 0.8966 400 T 0.8966 401 S 0.8375 402 S 0.8279 403 V 0.8565 404 P 0.8565 405 T 0.8828 406 V 0.8828 407 V 0.8828 408 T 0.8623 409 T 0.8741 410 G 0.8942 411 I 0.8894 412 H 0.8530 413 H 0.7672 414 Q 0.8279 415 P 0.7951 416 P 0.8085 417 P 0.8655 418 A 0.8235 419 P 0.8375 420 P 0.8375 421 S 0.8493 422 L 0.9081 423 F 0.8462 424 T 0.8596 425 A 0.8493 426 D 0.8493 427 T 0.8162 428 Y 0.8162 429 D 0.8343 430 T 0.7505 431 D 0.7369 432 G 0.7505 433 Y 0.8085 434 N 0.8828 435 P 0.8792 436 E 0.9013 437 A 0.8681 438 P 0.7799 439 S 0.8741 440 I 0.8565 441 T 0.8530 442 N 0.7799 443 T 0.7718 444 S 0.8421 445 R 0.8530 446 P 0.8375 447 M 0.8462 448 Y 0.8681 449 R 0.8013 450 H 0.7289 451 R 0.8085 452 V 0.7415 453 H 0.7331 454 A 0.7209 455 Q 0.7289 456 R 0.7369 457 P 0.6851 458 N 0.7289 459 L 0.7595 460 I 0.7755 461 G 0.7951 462 L 0.7951 463 T 0.8530 464 S 0.8462 465 G 0.8765 466 D 0.8765 467 M 0.8792 468 D 0.8596 469 L 0.8462 470 P 0.8853 471 P 0.9081 472 R 0.9057 473 E 0.8942 474 K 0.8493 475 P 0.8013 476 P 0.8013 477 N 0.7843 478 K 0.8198 479 S 0.8013 480 S 0.8596 481 M 0.8313 482 R 0.8125 483 I 0.8085 484 V 0.7120 485 V 0.7209 486 D 0.6906 487 S 0.6620 488 E 0.6576 489 S 0.6948 490 R 0.6991 491 K 0.6269 492 R 0.6948 493 T 0.6948 494 I 0.7718 495 G 0.8162 496 S 0.8655 497 G 0.7505 498 E 0.6375 499 P 0.6322 500 G 0.6269 501 V 0.6576 502 P 0.6806 503 T 0.5533 504 K 0.5665 505 K 0.6620 506 T 0.6576 507 W 0.6806 508 F 0.6712 509 D 0.6906 510 K 0.6576 511 P 0.5382 512 N 0.6183 513 F 0.5807 514 N 0.5707 515 R 0.5139 516 T 0.5296 517 N 0.4330 518 S 0.5419 519 P 0.6755 520 G 0.6755 521 F 0.6948 522 Q 0.6712 523 K 0.6482 524 K 0.6806 525 V 0.6712 526 Q 0.5807 527 F 0.5854 528 G 0.5620 529 N 0.5017 530 E 0.5017 531 N 0.5296 532 T 0.6531 533 K 0.5493 534 L 0.5707 535 E 0.5992 536 L 0.5665 537 R 0.5493 538 K 0.6661 539 V 0.5707 540 P 0.5707 541 P 0.5707 542 E 0.5665 543 L 0.4619 544 N 0.4619 545 N 0.5342 546 I 0.4330 547 S 0.5055 548 K 0.5017 549 L 0.4369 550 N 0.4369 551 E 0.4256 552 H 0.3356 553 F 0.3392 554 S 0.3494 555 R 0.3182 556 F 0.2292 557 G 0.3149 558 T 0.3215 559 L 0.3356 560 V 0.4256 561 N 0.4149 562 L 0.4149 563 Q 0.3840 564 V 0.4087 565 A 0.3392 566 Y 0.3426 567 N 0.3356 568 G 0.3117 569 D 0.3117 570 P 0.2988 571 E 0.3599 572 G 0.3494 573 A 0.3910 574 L 0.3774 575 I 0.4256 576 Q 0.4256 577 F 0.4256 578 A 0.4087 579 T 0.4017 580 Y 0.3910 581 E 0.3740 582 E 0.3460 583 A 0.2849 584 K 0.2364 585 K 0.3117 586 A 0.3983 587 I 0.3983 588 S 0.3948 589 S 0.3392 590 T 0.3321 591 E 0.3529 592 A 0.2715 593 V 0.1823 594 L 0.2129 595 N 0.2193 596 N 0.2328 597 R 0.2541 598 F 0.3215 599 I 0.3286 600 K 0.3356 601 V 0.3392 602 Y 0.2645 603 W 0.2884 604 H 0.3460 605 R 0.4149 606 E 0.3983 607 G 0.4119 608 S 0.4051 609 T 0.4369 610 Q 0.4901 611 Q 0.4979 612 L 0.6043 613 Q 0.6136 614 T 0.6531 615 T 0.6375 616 S 0.6322 617 P 0.6620 618 K 0.5533 619 V 0.4831 620 M 0.5139 621 Q 0.4441 622 P 0.3774 623 L 0.4441 624 V 0.4441 625 Q 0.4369 626 Q 0.3704 627 P 0.3704 628 I 0.3529 629 L 0.3631 630 P 0.3566 631 V 0.3840 632 V 0.4119 633 K 0.3215 634 Q 0.4220 635 S 0.4801 636 V 0.4725 637 K 0.4725 638 E 0.3599 639 R 0.4476 640 L 0.5533 641 G 0.4940 642 P 0.5707 643 V 0.6227 644 P 0.6269 645 S 0.6227 646 S 0.5901 647 T 0.6755 648 I 0.6755 649 E 0.6755 650 P 0.5707 651 A 0.7080 652 E 0.7080 653 A 0.6851 654 Q 0.6851 655 S 0.6482 656 A 0.6482 657 S 0.5620 658 S 0.5577 659 D 0.5854 660 L 0.5707 661 P 0.5456 662 Q 0.5854 663 N 0.4940 664 V 0.5254 665 T 0.4256 666 K 0.3740 667 L 0.3948 668 S 0.3948 669 V 0.4256 670 K 0.4119 671 D 0.4256 672 R 0.3910 673 L 0.3704 674 G 0.3566 675 F 0.4220 676 V 0.4186 677 S 0.3631 678 K 0.3667 679 P 0.3667 680 S 0.4256 681 V 0.4256 682 S 0.4149 683 A 0.4087 684 T 0.4119 685 E 0.4087 686 K 0.5017 687 V 0.5665 688 L 0.5017 689 S 0.4292 690 T 0.4149 691 S 0.4476 692 T 0.4864 693 G 0.4685 694 L 0.4292 695 T 0.4256 696 K 0.4017 697 T 0.3840 698 V 0.4441 699 Y 0.5055 700 N 0.5055 701 P 0.4441 702 A 0.3840 703 A 0.3321 704 L 0.3321 705 K 0.3948 706 A 0.3948 707 A 0.3774 708 Q 0.3215 709 K 0.3840 710 T 0.4766 711 L 0.4766 712 L 0.4507 713 V 0.4476 714 S 0.4685 715 T 0.5296 716 S 0.5296 717 A 0.5456 718 V 0.5758 719 D 0.5807 720 N 0.5577 721 N 0.4901 722 E 0.5533 723 A 0.5533 724 Q 0.6269 725 K 0.6322 726 K 0.6375 727 K 0.5665 728 Q 0.5992 729 E 0.6712 730 A 0.6661 731 L 0.6375 732 K 0.6183 733 L 0.6183 734 Q 0.5533 735 Q 0.4831 736 D 0.4940 737 V 0.4940 738 R 0.5211 739 K 0.4409 740 R 0.4409 741 K 0.4582 742 Q 0.5211 743 E 0.5211 744 I 0.5758 745 L 0.5017 746 E 0.4220 747 K 0.4149 748 H 0.4652 749 I 0.3983 750 E 0.4051 751 T 0.3983 752 Q 0.4186 753 K 0.4119 754 M 0.4051 755 L 0.4652 756 I 0.5254 757 S 0.5139 758 K 0.5254 759 L 0.5055 760 E 0.5901 761 K 0.5577 762 N 0.5620 763 K 0.4766 764 T 0.4685 765 M 0.4801 766 K 0.5456 767 S 0.5665 768 E 0.5665 769 D 0.5139 770 K 0.5176 771 A 0.5139 772 E 0.5139 773 I 0.5139 774 M 0.4441 775 K 0.4441 776 T 0.4619 777 L 0.4017 778 E 0.4017 779 V 0.3983 780 L 0.3983 781 T 0.3494 782 K 0.3740 783 N 0.3494 784 I 0.4051 785 T 0.4220 786 K 0.4582 787 L 0.4582 788 K 0.5254 789 D 0.4541 790 E 0.4441 791 V 0.5456 792 K 0.5456 793 A 0.5493 794 A 0.4582 795 S 0.5342 796 P 0.5342 797 G 0.5342 798 R 0.6183 799 C 0.6269 800 L 0.6089 801 P 0.6136 802 K 0.6851 803 S 0.6851 804 I 0.6322 805 K 0.5758 806 T 0.5758 807 K 0.5382 808 T 0.5419 809 Q 0.4685 810 M 0.5419 811 Q 0.5419 812 K 0.4292 813 E 0.4256 814 L 0.4220 815 L 0.4801 816 D 0.4864 817 T 0.4652 818 E 0.4652 819 L 0.4685 820 D 0.4652 821 L 0.4220 822 Y 0.4186 823 K 0.4220 824 K 0.3529 825 M 0.4149 826 Q 0.4766 827 A 0.4725 828 G 0.3948 829 E 0.3948 830 E 0.4619 831 V 0.3910 832 T 0.4652 833 E 0.4685 834 L 0.4801 835 R 0.4619 836 R 0.4541 837 K 0.4441 838 Y 0.4619 839 T 0.4619 840 E 0.3872 841 L 0.3182 842 Q 0.3740 843 L 0.3740 844 E 0.3667 845 A 0.4330 846 A 0.4330 847 K 0.4330 848 R 0.4369 849 G 0.4369 850 I 0.4507 851 L 0.4441 852 S 0.5139 853 S 0.5055 854 G 0.5854 855 R 0.5758 856 G 0.5758 857 R 0.5342 858 G 0.5533 859 I 0.5493 860 H 0.5493 861 S 0.6427 862 R 0.7250 863 G 0.7250 864 R 0.7209 865 G 0.7250 866 A 0.7163 867 V 0.7209 868 H 0.7163 869 G 0.7163 870 R 0.7369 871 G 0.7629 872 R 0.7629 873 G 0.7799 874 R 0.7547 875 G 0.6906 876 R 0.6136 877 G 0.6576 878 R 0.7415 879 G 0.7163 880 V 0.7595 881 P 0.7547 882 G 0.7289 883 H 0.6482 884 A 0.6620 885 V 0.5665 886 V 0.5707 887 D 0.5533 888 H 0.4541 889 R 0.4652 890 P 0.4766 891 R 0.5382 892 A 0.5098 893 L 0.4979 894 E 0.4979 895 I 0.5296 896 S 0.5176 897 A 0.5098 898 F 0.5419 899 T 0.5419 900 E 0.4541 901 S 0.4051 902 D 0.4220 903 R 0.3740 904 E 0.4441 905 D 0.4441 906 L 0.4476 907 L 0.4582 908 P 0.4831 909 H 0.5098 910 F 0.5176 911 A 0.4330 912 Q 0.4409 913 Y 0.4409 914 G 0.4507 915 E 0.4409 916 I 0.3667 917 E 0.4441 918 D 0.4940 919 C 0.4051 920 Q 0.3286 921 I 0.4220 922 D 0.3529 923 D 0.3321 924 S 0.4087 925 S 0.3910 926 L 0.3667 927 H 0.4441 928 A 0.4149 929 V 0.4186 930 I 0.4685 931 T 0.4409 932 F 0.4940 933 K 0.4330 934 T 0.4369 935 R 0.4409 936 A 0.4220 937 E 0.4766 938 A 0.3807 939 E 0.3840 940 A 0.4409 941 A 0.5254 942 A 0.5254 943 V 0.5493 944 H 0.5493 945 G 0.4685 946 A 0.4725 947 R 0.3948 948 F 0.3948 949 K 0.3983 950 G 0.4256 951 Q 0.3872 952 D 0.4119 953 L 0.4369 954 K 0.4220 955 L 0.4149 956 A 0.3948 957 W 0.3599 958 N 0.3840 959 K 0.4801 960 P 0.5017 961 V 0.5139 962 T 0.4441 963 N 0.4507 964 I 0.5577 965 S 0.5854 966 A 0.6948 967 V 0.7289 968 E 0.8493 969 T 0.7369 970 E 0.7629 971 E 0.7415 972 V 0.8162 973 E 0.8085 974 P 0.7209 975 D 0.7331 976 E 0.7459 977 E 0.7799 978 E 0.8313 979 F 0.7459 980 Q 0.6531 981 E 0.6482 982 E 0.6482 983 S 0.7369 984 L 0.7331 985 V 0.7120 986 D 0.7209 987 D 0.7250 988 S 0.7250 989 L 0.7250 990 L 0.8375 991 Q 0.8421 992 D 0.8235 993 D 0.7799 994 D 0.7799 995 E 0.7595 996 E 0.7951 997 E 0.7505 998 E 0.7289 999 D 0.7209 1000 N 0.8013 1001 E 0.8765 1002 S 0.8655 1003 R 0.8462 1004 S 0.8235 1005 W 0.7951 1006 R 0.7505 1007 R 0.6991