# IUPred2A: context-dependent prediction of protein disorder as a function of redox state and protein binding # Balint Meszaros, Gabor Erdos, Zsuzsanna Dosztanyi # Nucleic Acids Research 2018;46(W1):W329-W337. # # Prediction type: long # Prediction output # POS RES IUPRED2 1 M 0.9783 2 R 0.9783 3 N 0.9783 4 S 0.9519 5 E 0.9106 6 E 0.9168 7 Q 0.9168 8 P 0.8741 9 S 0.8235 10 G 0.8343 11 G 0.8530 12 T 0.8681 13 T 0.8125 14 V 0.8013 15 L 0.7163 16 Q 0.7120 17 R 0.7120 18 L 0.7415 19 L 0.7036 20 Q 0.7163 21 E 0.7250 22 Q 0.7163 23 L 0.7080 24 R 0.6183 25 Y 0.6136 26 G 0.6620 27 N 0.5577 28 P 0.5807 29 S 0.6576 30 E 0.7289 31 N 0.6991 32 R 0.6906 33 S 0.6851 34 L 0.7672 35 L 0.7718 36 A 0.8741 37 I 0.8942 38 H 0.8125 39 Q 0.8125 40 Q 0.8125 41 A 0.8013 42 T 0.7916 43 G 0.7951 44 N 0.8050 45 G 0.8894 46 P 0.9269 47 P 0.9519 48 F 0.9751 49 P 0.9717 50 S 0.9751 51 G 0.9593 52 S 0.9415 53 G 0.9396 54 N 0.9547 55 P 0.9519 56 G 0.9577 57 P 0.9503 58 Q 0.9433 59 S 0.9725 60 D 0.9657 61 V 0.9415 62 L 0.9106 63 S 0.9013 64 P 0.9081 65 Q 0.8894 66 D 0.8530 67 H 0.8493 68 H 0.8198 69 Q 0.8279 70 Q 0.8596 71 L 0.8462 72 V 0.8920 73 A 0.9287 74 H 0.9329 75 A 0.8655 76 A 0.8655 77 R 0.8493 78 Q 0.8421 79 E 0.8343 80 P 0.7718 81 Q 0.6755 82 G 0.7250 83 Q 0.7982 84 E 0.8125 85 I 0.8013 86 Q 0.7547 87 S 0.7718 88 E 0.8050 89 N 0.8050 90 L 0.7718 91 I 0.7369 92 M 0.7459 93 E 0.7595 94 K 0.7672 95 Q 0.7672 96 L 0.7843 97 S 0.8125 98 P 0.8162 99 R 0.7163 100 M 0.7120 101 Q 0.7951 102 N 0.8462 103 N 0.8623 104 E 0.7951 105 E 0.8050 106 L 0.8013 107 P 0.8655 108 T 0.7916 109 Y 0.6482 110 E 0.6482 111 E 0.6806 112 A 0.6851 113 K 0.6806 114 V 0.6806 115 Q 0.6427 116 S 0.6269 117 Q 0.6322 118 Y 0.5951 119 F 0.5665 120 R 0.6531 121 G 0.5296 122 Q 0.4409 123 Q 0.4017 124 H 0.4051 125 A 0.4652 126 S 0.4051 127 V 0.4051 128 G 0.4119 129 A 0.4979 130 A 0.5992 131 F 0.5620 132 Y 0.5665 133 V 0.5577 134 T 0.5620 135 G 0.5493 136 V 0.5807 137 T 0.6183 138 N 0.6906 139 Q 0.6136 140 K 0.6531 141 M 0.6806 142 R 0.7163 143 T 0.8198 144 E 0.8920 145 G 0.8942 146 R 0.8894 147 P 0.9106 148 S 0.9168 149 V 0.9126 150 Q 0.9168 151 R 0.9249 152 L 0.9381 153 N 0.9039 154 P 0.9057 155 G 0.9106 156 K 0.8655 157 M 0.8596 158 H 0.8421 159 Q 0.8462 160 D 0.8966 161 E 0.8421 162 G 0.8421 163 L 0.8894 164 R 0.8313 165 D 0.8013 166 L 0.8085 167 K 0.8162 168 Q 0.7881 169 G 0.7415 170 H 0.7415 171 V 0.6851 172 R 0.6712 173 S 0.5901 174 L 0.6427 175 S 0.6427 176 E 0.6183 177 R 0.6991 178 L 0.6269 179 M 0.6136 180 Q 0.5807 181 M 0.5807 182 S 0.6851 183 L 0.7120 184 A 0.6427 185 T 0.7163 186 S 0.7163 187 G 0.6806 188 V 0.7080 189 K 0.7036 190 A 0.7331 191 H 0.7547 192 P 0.8085 193 P 0.8198 194 V 0.8894 195 T 0.9106 196 S 0.9190 197 A 0.8828 198 P 0.8013 199 L 0.8565 200 S 0.8681 201 P 0.8991 202 P 0.8942 203 Q 0.8765 204 P 0.8596 205 N 0.8966 206 D 0.9013 207 L 0.8279 208 Y 0.7595 209 K 0.7331 210 N 0.7755 211 P 0.7916 212 T 0.7672 213 S 0.7672 214 S 0.6851 215 S 0.6906 216 E 0.6906 217 F 0.6851 218 Y 0.7629 219 K 0.8493 220 A 0.7951 221 Q 0.7843 222 G 0.7595 223 P 0.7289 224 L 0.7415 225 P 0.7547 226 N 0.7672 227 Q 0.7629 228 H 0.8741 229 S 0.9396 230 L 0.9519 231 K 0.9634 232 G 0.9168 233 M 0.9287 234 E 0.8530 235 H 0.8966 236 R 0.8853 237 G 0.8565 238 P 0.8655 239 P 0.8765 240 P 0.8920 241 E 0.9230 242 Y 0.8942 243 P 0.8530 244 F 0.7881 245 K 0.7755 246 G 0.7916 247 M 0.8013 248 P 0.8050 249 P 0.8050 250 Q 0.7881 251 S 0.7755 252 V 0.6531 253 V 0.6531 254 C 0.6183 255 K 0.7415 256 P 0.7547 257 Q 0.7595 258 E 0.7209 259 P 0.7120 260 G 0.7036 261 H 0.7080 262 F 0.7163 263 Y 0.7843 264 S 0.8375 265 E 0.9151 266 H 0.9190 267 R 0.9151 268 L 0.8681 269 N 0.8343 270 Q 0.8198 271 P 0.7209 272 G 0.7250 273 R 0.8375 274 T 0.9190 275 E 0.9329 276 G 0.9329 277 Q 0.8741 278 L 0.8765 279 M 0.9057 280 R 0.8894 281 Y 0.8853 282 Q 0.8853 283 H 0.8713 284 P 0.8765 285 P 0.8894 286 E 0.8235 287 Y 0.8198 288 G 0.7459 289 A 0.8313 290 A 0.8050 291 R 0.7982 292 P 0.8713 293 A 0.8655 294 Q 0.8713 295 D 0.8493 296 I 0.8375 297 S 0.8530 298 L 0.9211 299 P 0.9168 300 L 0.9381 301 S 0.9433 302 A 0.9396 303 R 0.9287 304 N 0.9039 305 S 0.8966 306 Q 0.8828 307 P 0.9287 308 H 0.9329 309 S 0.9577 310 P 0.9211 311 T 0.9577 312 S 0.9346 313 S 0.9126 314 L 0.9151 315 T 0.9039 316 S 0.9211 317 G 0.9287 318 G 0.9151 319 S 0.9057 320 L 0.9126 321 P 0.8530 322 L 0.8530 323 L 0.8741 324 Q 0.8655 325 S 0.9081 326 P 0.9168 327 P 0.9308 328 S 0.8920 329 T 0.8375 330 R 0.8623 331 L 0.9106 332 S 0.8991 333 P 0.9329 334 A 0.9657 335 R 0.9664 336 H 0.9664 337 P 0.9519 338 L 0.9488 339 V 0.9168 340 P 0.9329 341 N 0.9308 342 Q 0.9664 343 G 0.9684 344 D 0.9649 345 H 0.9717 346 S 0.9381 347 A 0.8942 348 H 0.8966 349 L 0.9362 350 P 0.9649 351 R 0.9488 352 P 0.9488 353 Q 0.9473 354 Q 0.9473 355 H 0.9457 356 F 0.9473 357 L 0.9039 358 P 0.9151 359 N 0.8596 360 Q 0.9039 361 A 0.8872 362 H 0.9039 363 Q 0.8872 364 G 0.8279 365 D 0.8198 366 H 0.8050 367 Y 0.8872 368 R 0.9269 369 L 0.9126 370 S 0.9081 371 Q 0.9057 372 P 0.9190 373 G 0.9126 374 L 0.9126 375 S 0.9190 376 Q 0.9168 377 Q 0.9151 378 Q 0.9621 379 Q 0.9664 380 Q 0.9816 381 Q 0.9844 382 Q 0.9844 383 Q 0.9801 384 Q 0.9797 385 H 0.9887 386 H 0.9889 387 H 0.9889 388 H 0.9887 389 H 0.9903 390 H 0.9903 391 H 0.9901 392 Q 0.9901 393 Q 0.9912 394 Q 0.9912 395 Q 0.9911 396 Q 0.9892 397 Q 0.9762 398 Q 0.9725 399 P 0.9649 400 Q 0.9503 401 Q 0.9547 402 Q 0.9488 403 P 0.9381 404 G 0.9381 405 E 0.9503 406 A 0.9473 407 Y 0.9457 408 S 0.9346 409 A 0.9329 410 M 0.8655 411 P 0.8655 412 R 0.8853 413 A 0.8279 414 Q 0.8279 415 P 0.8085 416 S 0.8198 417 S 0.8623 418 A 0.8565 419 S 0.8421 420 Y 0.7881 421 Q 0.7369 422 P 0.7036 423 V 0.6991 424 P 0.6991 425 A 0.6991 426 D 0.6620 427 P 0.6427 428 F 0.5620 429 A 0.5854 430 I 0.5098 431 V 0.5254 432 S 0.5176 433 R 0.5017 434 A 0.5707 435 Q 0.5493 436 Q 0.5665 437 M 0.5620 438 V 0.4619 439 E 0.5533 440 I 0.5665 441 L 0.6620 442 S 0.6576 443 D 0.6576 444 E 0.6620 445 N 0.5707 446 R 0.4901 447 N 0.4864 448 L 0.4979 449 R 0.4979 450 Q 0.4801 451 E 0.5456 452 L 0.5456 453 E 0.5493 454 G 0.5254 455 C 0.4619 456 Y 0.4476 457 E 0.4507 458 K 0.4369 459 V 0.4369 460 A 0.4369 461 R 0.4292 462 L 0.3740 463 Q 0.4330 464 K 0.4330 465 V 0.4149 466 E 0.4330 467 T 0.5017 468 E 0.5139 469 I 0.4582 470 Q 0.4582 471 R 0.4652 472 V 0.4685 473 S 0.5342 474 E 0.5342 475 A 0.5342 476 Y 0.5951 477 E 0.5951 478 N 0.5707 479 L 0.4979 480 V 0.5707 481 K 0.5620 482 S 0.5456 483 S 0.5992 484 S 0.5901 485 K 0.5992 486 R 0.6043 487 E 0.6043 488 A 0.6043 489 L 0.5854 490 E 0.6661 491 K 0.6427 492 A 0.6375 493 M 0.6269 494 R 0.6043 495 N 0.6227 496 K 0.6427 497 L 0.5342 498 E 0.5419 499 G 0.5493 500 E 0.6427 501 I 0.5493 502 R 0.5493 503 R 0.5707 504 M 0.5807 505 H 0.5098 506 D 0.4979 507 F 0.5098 508 N 0.5533 509 R 0.5665 510 D 0.5533 511 L 0.5493 512 R 0.5577 513 E 0.5456 514 R 0.5533 515 L 0.5620 516 E 0.5419 517 T 0.4619 518 A 0.5533 519 N 0.5382 520 K 0.5456 521 Q 0.5342 522 L 0.6183 523 A 0.6322 524 E 0.6136 525 K 0.6136 526 E 0.7080 527 Y 0.6089 528 E 0.6043 529 G 0.6322 530 S 0.5342 531 E 0.4541 532 D 0.4409 533 T 0.4979 534 R 0.5342 535 K 0.5254 536 T 0.5296 537 I 0.5296 538 S 0.6089 539 Q 0.5951 540 L 0.5951 541 F 0.5854 542 A 0.5901 543 K 0.5758 544 N 0.4979 545 K 0.5055 546 E 0.4979 547 S 0.4901 548 Q 0.4979 549 R 0.4831 550 E 0.4864 551 K 0.5382 552 E 0.6322 553 K 0.6576 554 L 0.6712 555 E 0.6712 556 A 0.6755 557 E 0.6851 558 L 0.6851 559 A 0.6755 560 T 0.6755 561 A 0.7036 562 R 0.6183 563 S 0.6183 564 T 0.5342 565 N 0.5992 566 E 0.6089 567 D 0.6322 568 Q 0.6089 569 R 0.6089 570 R 0.6322 571 H 0.6427 572 I 0.6427 573 E 0.6576 574 I 0.6322 575 R 0.6183 576 D 0.5296 577 Q 0.4685 578 A 0.4582 579 L 0.3948 580 S 0.4051 581 N 0.4149 582 A 0.3948 583 Q 0.4017 584 A 0.3948 585 K 0.4619 586 V 0.4619 587 V 0.4582 588 K 0.4017 589 L 0.3494 590 E 0.3566 591 E 0.3599 592 E 0.3392 593 L 0.2988 594 K 0.3019 595 K 0.3117 596 K 0.3053 597 Q 0.3599 598 V 0.4149 599 Y 0.4051 600 V 0.4051 601 D 0.3460 602 K 0.3426 603 V 0.2783 604 E 0.3392 605 K 0.3286 606 M 0.3182 607 Q 0.2541 608 Q 0.2575 609 A 0.3053 610 L 0.3667 611 V 0.4292 612 Q 0.4256 613 L 0.3667 614 Q 0.4292 615 A 0.4409 616 A 0.4409 617 C 0.3872 618 E 0.3774 619 K 0.3807 620 R 0.3910 621 E 0.3872 622 Q 0.4507 623 L 0.4441 624 E 0.5211 625 H 0.4476 626 R 0.4725 627 L 0.4901 628 R 0.4940 629 T 0.4831 630 R 0.4119 631 L 0.4186 632 E 0.4119 633 R 0.4017 634 E 0.4685 635 L 0.4619 636 E 0.4582 637 S 0.3910 638 L 0.4619 639 R 0.5017 640 I 0.5055 641 Q 0.5254 642 Q 0.5342 643 R 0.5254 644 Q 0.5419 645 G 0.4541 646 N 0.5419 647 C 0.5098 648 Q 0.4864 649 P 0.5382 650 T 0.4725 651 N 0.5342 652 V 0.5382 653 S 0.4619 654 E 0.3983 655 Y 0.3910 656 N 0.3983 657 A 0.3807 658 A 0.4652 659 A 0.4685 660 L 0.4292 661 M 0.3460 662 E 0.2645 663 L 0.3019 664 L 0.2292 665 R 0.2258 666 E 0.2817 667 K 0.2752 668 E 0.2783 669 E 0.3019 670 R 0.3149 671 I 0.2884 672 L 0.3149 673 A 0.3087 674 L 0.3740 675 E 0.3667 676 A 0.3053 677 D 0.3019 678 M 0.3117 679 T 0.3182 680 K 0.2541 681 W 0.2364 682 E 0.3117 683 Q 0.3948 684 K 0.3249 685 Y 0.3774 686 L 0.3019 687 E 0.3321 688 E 0.3019 689 N 0.2988 690 V 0.2715 691 M 0.2783 692 R 0.3149 693 H 0.2884 694 F 0.2645 695 A 0.2752 696 L 0.3460 697 D 0.4256 698 A 0.4220 699 A 0.4186 700 A 0.3494 701 T 0.3356 702 V 0.3529 703 A 0.3704 704 A 0.3566 705 Q 0.4801 706 R 0.5139 707 D 0.6043 708 T 0.5951 709 T 0.5296 710 V 0.5620 711 I 0.5992 712 S 0.5665 713 H 0.5577 714 S 0.5992 715 P 0.5992 716 N 0.5901 717 T 0.5017 718 S 0.4979 719 Y 0.4864 720 D 0.4979 721 T 0.5807 722 A 0.6991 723 L 0.7163 724 E 0.5992 725 A 0.5139 726 R 0.4507 727 I 0.4149 728 Q 0.4220 729 K 0.4149 730 E 0.4940 731 E 0.4087 732 E 0.3356 733 E 0.3667 734 I 0.4051 735 L 0.4087 736 M 0.4330 737 A 0.4330 738 N 0.4330 739 K 0.4220 740 R 0.4292 741 C 0.3494 742 L 0.3426 743 D 0.3053 744 M 0.3053 745 E 0.3019 746 G 0.2951 747 R 0.3356 748 I 0.3566 749 K 0.3566 750 T 0.3392 751 L 0.3182 752 H 0.3215 753 A 0.3840 754 Q 0.3215 755 I 0.2884 756 I 0.2849 757 E 0.2951 758 K 0.2988 759 D 0.3704 760 A 0.3774 761 M 0.3667 762 I 0.4507 763 K 0.4766 764 V 0.5017 765 L 0.4831 766 Q 0.5707 767 Q 0.6948 768 R 0.6906 769 S 0.6089 770 R 0.5951 771 K 0.5296 772 E 0.5296 773 P 0.6269 774 S 0.6755 775 K 0.7120 776 T 0.7843 777 E 0.7718 778 Q 0.6806 779 L 0.6531 780 S 0.6531 781 C 0.5533 782 M 0.5577 783 R 0.5533 784 P 0.4940 785 A 0.4940 786 K 0.4979 787 S 0.4979 788 L 0.4220 789 M 0.3494 790 S 0.4087 791 I 0.4220 792 S 0.4979 793 N 0.5211 794 A 0.5211 795 G 0.4220 796 S 0.4476 797 G 0.4541 798 L 0.4507 799 L 0.5533 800 S 0.4940 801 H 0.4725 802 S 0.5707 803 S 0.5992 804 T 0.5807 805 L 0.6183 806 T 0.6375 807 G 0.6531 808 S 0.6482 809 P 0.7250 810 I 0.7036 811 M 0.6991 812 E 0.6851 813 E 0.6851 814 K 0.5951 815 R 0.5951 816 D 0.5807 817 D 0.5017 818 K 0.4330 819 S 0.4369 820 W 0.4087 821 K 0.4940 822 G 0.4220 823 S 0.4149 824 L 0.3667 825 G 0.3948 826 I 0.2951 827 L 0.2328 828 L 0.2503 829 G 0.2503 830 G 0.2541 831 D 0.3631 832 Y 0.3631 833 R 0.3948 834 A 0.3426 835 E 0.4409 836 Y 0.4685 837 V 0.5493 838 P 0.6375 839 S 0.7595 840 T 0.6755 841 P 0.5854 842 S 0.5620 843 P 0.6482 844 V 0.6576 845 P 0.6948 846 P 0.6620 847 S 0.7843 848 T 0.8375 849 P 0.8013 850 L 0.8198 851 L 0.8375 852 S 0.7163 853 A 0.7120 854 H 0.6806 855 S 0.7672 856 K 0.7369 857 T 0.7289 858 G 0.7505 859 S 0.7459 860 R 0.7163 861 D 0.8198 862 C 0.8792 863 S 0.8894 864 T 0.9081 865 Q 0.8991 866 T 0.8792 867 E 0.8565 868 R 0.7951 869 G 0.7595 870 T 0.7951 871 E 0.6755 872 S 0.6482 873 N 0.6755 874 K 0.7209 875 T 0.6712 876 A 0.6851 877 A 0.6043 878 V 0.5296 879 A 0.4831 880 P 0.4507 881 I 0.4149 882 S 0.3948 883 V 0.3704 884 P 0.3286 885 A 0.3019 886 P 0.2129 887 V 0.2503 888 A 0.2503 889 A 0.3117 890 A 0.3117 891 A 0.2575 892 T 0.3460 893 A 0.2645 894 A 0.3249 895 A 0.3053 896 I 0.3460 897 T 0.2817 898 A 0.2849 899 T 0.2849 900 A 0.2884 901 A 0.2884 902 T 0.3460 903 I 0.2849 904 T 0.2849 905 T 0.2609 906 T 0.2609 907 M 0.3149 908 V 0.2817 909 A 0.2817 910 A 0.2470 911 A 0.3019 912 P 0.3019 913 V 0.2645 914 A 0.3182 915 V 0.2817 916 A 0.2470 917 A 0.2680 918 A 0.2988 919 A 0.3807 920 A 0.3807 921 P 0.4186 922 A 0.4220 923 A 0.3631 924 A 0.3948 925 A 0.4330 926 A 0.4619 927 P 0.4652 928 S 0.4685 929 P 0.4441 930 A 0.4725 931 T 0.5342 932 A 0.4725 933 A 0.4766 934 A 0.4801 935 T 0.5176 936 A 0.5807 937 A 0.5139 938 A 0.5139 939 V 0.4864 940 S 0.4292 941 P 0.4292 942 A 0.4186 943 A 0.3948 944 A 0.3948 945 G 0.4220 946 Q 0.3840 947 I 0.3840 948 P 0.3840 949 A 0.3529 950 A 0.3807 951 A 0.4087 952 S 0.3807 953 V 0.3807 954 A 0.3807 955 S 0.3807 956 A 0.3494 957 A 0.3019 958 A 0.3566 959 V 0.2752 960 A 0.3215 961 P 0.2951 962 S 0.2918 963 A 0.3182 964 A 0.3426 965 A 0.3426 966 A 0.3704 967 A 0.3667 968 A 0.4220 969 V 0.3910 970 Q 0.4766 971 V 0.4725 972 A 0.4725 973 P 0.4441 974 A 0.4051 975 A 0.3740 976 P 0.4292 977 A 0.3948 978 P 0.4507 979 V 0.4476 980 P 0.5419 981 A 0.4831 982 P 0.5176 983 A 0.5176 984 L 0.5098 985 V 0.5098 986 P 0.5419 987 V 0.4801 988 P 0.5419 989 A 0.4801 990 P 0.5707 991 A 0.5493 992 A 0.6183 993 A 0.5419 994 Q 0.6183 995 A 0.7209 996 S 0.7916 997 A 0.7250 998 P 0.8235 999 A 0.7629 1000 Q 0.7289 1001 T 0.6576 1002 Q 0.7289 1003 A 0.7755 1004 P 0.8375 1005 T 0.7881 1006 S 0.8462 1007 A 0.8565 1008 P 0.8991 1009 A 0.8872 1010 V 0.9249 1011 A 0.8942 1012 P 0.8375 1013 T 0.7881 1014 P 0.8421 1015 A 0.7843 1016 P 0.8050 1017 T 0.7415 1018 P 0.8050 1019 T 0.7459 1020 P 0.7799 1021 A 0.8681 1022 V 0.8681 1023 A 0.8530 1024 Q 0.8493 1025 A 0.8462 1026 E 0.8765 1027 V 0.8765 1028 P 0.8828 1029 A 0.8713 1030 S 0.7982 1031 P 0.7718 1032 A 0.6991 1033 T 0.8013 1034 G 0.8279 1035 P 0.7331 1036 G 0.7799 1037 P 0.6427 1038 H 0.7415 1039 R 0.7369 1040 L 0.8085 1041 S 0.8050 1042 I 0.7916 1043 P 0.8530 1044 S 0.8493 1045 L 0.8681 1046 T 0.7881 1047 C 0.6755 1048 N 0.6661 1049 P 0.6375 1050 D 0.6427 1051 K 0.7369 1052 T 0.6620 1053 D 0.8013 1054 G 0.7843 1055 P 0.7799 1056 V 0.8565 1057 F 0.8681 1058 H 0.8681 1059 S 0.8713 1060 N 0.7718 1061 T 0.6620 1062 L 0.6806 1063 E 0.6948 1064 R 0.6851 1065 K 0.7080 1066 T 0.7163 1067 P 0.7595 1068 I 0.8741 1069 Q 0.8375 1070 I 0.7799 1071 L 0.7951 1072 G 0.6755 1073 Q 0.6851 1074 E 0.5533 1075 P 0.5211 1076 D 0.5098 1077 A 0.4801 1078 E 0.4256 1079 M 0.5055 1080 V 0.4541 1081 E 0.5456 1082 Y 0.6269 1083 L 0.5807 1084 I 0.5017